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Stabilization of Human Multidrug Resistance Protein 4 (MRP4/ABCC4) Using Novel Solubilization Agents

Membrane proteins (MPs) are important drug discovery targets for a wide range of diseases. However, elucidating the structure and function of native MP is notoriously challenging as their original structure has to be maintained once removed from the lipid bilayer. Conventionally, detergents have bee...

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Detalles Bibliográficos
Autores principales:	Hardy, David, Bill, Roslyn M., Rothnie, Alice J., Jawhari, Anass
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2019
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6873219/ https://www.ncbi.nlm.nih.gov/pubmed/31381456 http://dx.doi.org/10.1177/2472555219867074

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