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Predominantly Antibody-Deficient Patients With Non-infectious Complications Have Reduced Naive B, Treg, Th17, and Tfh17 Cells

Background: Patients with predominantly antibody deficiency (PAD) suffer from severe and recurrent infections that require lifelong immunoglobulin replacement and prophylactic antibiotic treatment. Disease incidence is estimated to be 1:25,000 worldwide, and up to 68% of patients develop non-infecti...

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Detalles Bibliográficos
Autores principales: Edwards, Emily S. J., Bosco, Julian J., Aui, Pei M., Stirling, Robert G., Cameron, Paul U., Chatelier, Josh, Hore-Lacy, Fiona, O'Hehir, Robyn E., van Zelm, Menno C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6873234/
https://www.ncbi.nlm.nih.gov/pubmed/31803177
http://dx.doi.org/10.3389/fimmu.2019.02593

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