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Predominantly Antibody-Deficient Patients With Non-infectious Complications Have Reduced Naive B, Treg, Th17, and Tfh17 Cells
Background: Patients with predominantly antibody deficiency (PAD) suffer from severe and recurrent infections that require lifelong immunoglobulin replacement and prophylactic antibiotic treatment. Disease incidence is estimated to be 1:25,000 worldwide, and up to 68% of patients develop non-infecti...
Autores principales: | Edwards, Emily S. J., Bosco, Julian J., Aui, Pei M., Stirling, Robert G., Cameron, Paul U., Chatelier, Josh, Hore-Lacy, Fiona, O'Hehir, Robyn E., van Zelm, Menno C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6873234/ https://www.ncbi.nlm.nih.gov/pubmed/31803177 http://dx.doi.org/10.3389/fimmu.2019.02593 |
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