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Impairment of NKG2D-Mediated Tumor Immunity by TGF-β
Transforming growth factor-β (TGF-β) suppresses innate and adaptive immune responses via multiple mechanisms. TGF-β also importantly contributes to the formation of an immunosuppressive tumor microenvironment thereby promoting tumor growth. Amongst others, TGF-β impairs tumor recognition by cytotoxi...
Autores principales: | Lazarova, Mariya, Steinle, Alexander |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6873348/ https://www.ncbi.nlm.nih.gov/pubmed/31803194 http://dx.doi.org/10.3389/fimmu.2019.02689 |
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