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Better quality score compression through sequence-based quality smoothing

MOTIVATION: Current NGS techniques are becoming exponentially cheaper. As a result, there is an exponential growth of genomic data unfortunately not followed by an exponential growth of storage, leading to the necessity of compression. Most of the entropy of NGS data lies in the quality values assoc...

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Detalles Bibliográficos
Autores principales: Shibuya, Yoshihiro, Comin, Matteo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6873394/
https://www.ncbi.nlm.nih.gov/pubmed/31757199
http://dx.doi.org/10.1186/s12859-019-2883-5