Multiplex nucleotide editing by high-fidelity Cas9 variants with improved efficiency in rice

BACKGROUND: Application of the CRISPR/Cas9 system or its derived base editors enables targeted genome modification, thereby providing a programmable tool to exploit gene functions and to improve crop traits. RESULTS: We report that PmCDA1 is much more efficient than rAPOBEC1 when fused to CRISPR/Cas...

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Detalles Bibliográficos
Autores principales: Xu, Wen, Song, Wei, Yang, Yongxing, Wu, Ying, Lv, Xinxin, Yuan, Shuang, Liu, Ya, Yang, Jinxiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6873407/
https://www.ncbi.nlm.nih.gov/pubmed/31752697
http://dx.doi.org/10.1186/s12870-019-2131-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6873407/
https://www.ncbi.nlm.nih.gov/pubmed/31752697
http://dx.doi.org/10.1186/s12870-019-2131-1

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