WDR5 inhibition halts metastasis dissemination by repressing the mesenchymal phenotype of breast cancer cells

BACKGROUND: Development of metastases and drug resistance are still a challenge for a successful systemic treatment in breast cancer (BC) patients. One of the mechanisms that confer metastatic properties to the cell relies in the epithelial-to-mesenchymal transition (EMT). Moreover, both EMT and met...

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Detalles Bibliográficos
Autores principales: Punzi, Simona, Balestrieri, Chiara, D’Alesio, Carolina, Bossi, Daniela, Dellino, Gaetano Ivan, Gatti, Elena, Pruneri, Giancarlo, Criscitiello, Carmen, Lovati, Giulia, Meliksetyan, Marine, Carugo, Alessandro, Curigliano, Giuseppe, Natoli, Gioacchino, Pelicci, Pier Giuseppe, Lanfrancone, Luisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6873410/
https://www.ncbi.nlm.nih.gov/pubmed/31752957
http://dx.doi.org/10.1186/s13058-019-1216-y

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