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Blood brain barrier leakage is not a consistent feature of white matter lesions in CADASIL

Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is a genetic paradigm of small vessel disease (SVD) caused by NOTCH3 mutations that stereotypically lead to the vascular accumulation of NOTCH3 around smooth muscle cells and pericytes. White matter...

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Detalles Bibliográficos
Autores principales: Rajani, Rikesh M., Ratelade, Julien, Domenga-Denier, Valérie, Hase, Yoshiki, Kalimo, Hannu, Kalaria, Raj N., Joutel, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6873485/
https://www.ncbi.nlm.nih.gov/pubmed/31753008
http://dx.doi.org/10.1186/s40478-019-0844-x

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