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Blood brain barrier leakage is not a consistent feature of white matter lesions in CADASIL
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is a genetic paradigm of small vessel disease (SVD) caused by NOTCH3 mutations that stereotypically lead to the vascular accumulation of NOTCH3 around smooth muscle cells and pericytes. White matter...
Autores principales: | Rajani, Rikesh M., Ratelade, Julien, Domenga-Denier, Valérie, Hase, Yoshiki, Kalimo, Hannu, Kalaria, Raj N., Joutel, Anne |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6873485/ https://www.ncbi.nlm.nih.gov/pubmed/31753008 http://dx.doi.org/10.1186/s40478-019-0844-x |
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