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Cytotoxic activity of crude extracts from Datura stramonium’s fungal endophytes against A549 lung carcinoma and UMG87 glioblastoma cell lines and LC-QTOF-MS/MS based metabolite profiling

BACKGROUND: Endophytic fungi are a proven source of bioactive secondary metabolites that may provide lead compounds for novel drug discovery. In this study, crude extracts from fungal endophytes isolated from Datura stramonium were evaluated for cytotoxic activity on two human cancer cell lines. MET...

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Detalles Bibliográficos
Autores principales:	Tapfuma, Kudzanai Ian, Uche-Okereafor, Nkemdinma, Sebola, Tendani Edith, Hussan, Raeesa, Mekuto, Lukhanyo, Makatini, Maya Mellisa, Green, Ezekiel, Mavumengwana, Vuyo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6873518/ https://www.ncbi.nlm.nih.gov/pubmed/31752824 http://dx.doi.org/10.1186/s12906-019-2752-9

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