Downregulation of class II phosphoinositide 3-kinase PI3K-C2β delays cell division and potentiates the effect of docetaxel on cancer cell growth

BACKGROUND: Alteration of signalling pathways regulating cell cycle progression is a common feature of cancer cells. Several drugs targeting distinct phases of the cell cycle have been developed but the inability of many of them to discriminate between normal and cancer cells has strongly limited th...

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Detalles Bibliográficos
Autores principales: Cisse, Ouma, Quraishi, Muzthahid, Gulluni, Federico, Guffanti, Federica, Mavrommati, Ioanna, Suthanthirakumaran, Methushaa, Oh, Lara C. R., Schlatter, Jessica N., Sarvananthan, Ambisha, Broggini, Massimo, Hirsch, Emilio, Falasca, Marco, Maffucci, Tania
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6873561/
https://www.ncbi.nlm.nih.gov/pubmed/31752944
http://dx.doi.org/10.1186/s13046-019-1472-9

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