Cargando…

Gegen Qinlian Decoction Ameliorates Hepatic Insulin Resistance by Silent Information Regulator1 (SIRT1)-Dependent Deacetylation of Forkhead Box O1 (FOXO1)

BACKGROUND: Gegen qinlian decoction (GGQLD) is a form of traditional Chinese medicine used for hundreds of years for its efficacy in treating diabetes. However, the mechanisms underlying the therapeutic effects of GGQLD on diabetes are still not clear. We aimed to evaluate the effect of GGQLD on hep...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sui, Miao, Chen, Guofang, Mao, Xiaodong, Wei, Xiao, Chen, Yu, Liu, Chao, Fan, Yaofu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	International Scientific Literature, Inc. 2019
Materias:	Animal Study
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6873633/ https://www.ncbi.nlm.nih.gov/pubmed/31719515 http://dx.doi.org/10.12659/MSM.919498

Ejemplares similares

Constituents, Pharmacokinetics, and Pharmacology of Gegen-Qinlian Decoction
por: Lu, Jing-Ze, et al.
Publicado: (2021)

Mechanism of Gegen Qinlian Decoction Regulating ABTB1 Expression in Colorectal Cancer Metastasis Based on PI3K/AKT/FOXO1 Pathway
por: Li, Feng, et al.
Publicado: (2022)

Exploring Anti-Type 2 Diabetes Mellitus Mechanism of Gegen Qinlian Decoction by Network Pharmacology and Experimental Validation
por: Bao, Weiping, et al.
Publicado: (2022)

Effect of Gegen Qinlian Decoction on Cardiac Gene Expression in Diabetic Mice
por: Han, Jing, et al.
Publicado: (2017)

Network Pharmacology-Based Study on the Mechanism of Gegen Qinlian Decoction against Colorectal Cancer
por: Fan, Qiaowei, et al.
Publicado: (2020)

Gegen Qinlian Decoction treatment of asymptomatic hyperuricemia by targeting circadian immune function
por: Wang, Xiaojun, et al.
Publicado: (2023)

Effect of Sleeve Gastrectomy on Glycometabolism via Forkhead Box O1 (FoxO1)/Lipocalin-2 (LCN2) Pathway
por: Liu, Zhi, et al.
Publicado: (2020)

Targeting Sirt1 in a rat model of high-fat diet-induced non-alcoholic fatty liver disease: Comparison of Gegen Qinlian decoction and resveratrol
por: Guo, Yi, et al.
Publicado: (2017)

Network Pharmacology–Based Analysis and Experimental Exploration of Antidiabetic Mechanisms of Gegen Qinlian Decoction
por: Xu, Yu, et al.
Publicado: (2021)

Scientific Evidence of Chinese Herbal Medicine (Gegen Qinlian Decoction) in the Treatment of Ulcerative Colitis
por: Huang, Jinke, et al.
Publicado: (2022)

Gegen Qinlian Decoction Relieves Ulcerative Colitis via Adjusting Dysregulated Nrf2/ARE Signaling
por: Lin, Chuan, et al.
Publicado: (2022)

Efficacy and Safety of Gegen Qinlian Decoction for Pediatric Diarrhea: A Systematic Review and Meta-Analysis
por: Wang, Dan, et al.
Publicado: (2022)

Gegen Qinlian Decoction Treats Diarrhea in Piglets by Modulating Gut Microbiota and Short-Chain Fatty Acids
por: Liu, Chang-Shun, et al.
Publicado: (2019)

Antidiabetic Effects of Gegen Qinlian Decoction via the Gut Microbiota Are Attributable to Its Key Ingredient Berberine
por: Xu, Xizhan, et al.
Publicado: (2020)

Gegen Qinlian decoction enhances the effect of PD-1 blockade in colorectal cancer with microsatellite stability by remodelling the gut microbiota and the tumour microenvironment
por: Lv, Ji, et al.
Publicado: (2019)

Gegen Qinlian Decoction Attenuates High-Fat Diet-Induced Steatohepatitis in Rats via Gut Microbiota
por: Guo, Yi, et al.
Publicado: (2018)

Based on Network Pharmacology to Explore the Molecular Targets and Mechanisms of Gegen Qinlian Decoction for the Treatment of Ulcerative Colitis
por: Wei, Meiqi, et al.
Publicado: (2020)

In Silico and In Vivo Studies on the Mechanisms of Chinese Medicine Formula (Gegen Qinlian Decoction) in the Treatment of Ulcerative Colitis
por: Liu, Xiaolu, et al.
Publicado: (2021)

Tissue distribution and integrated pharmacokinetic properties of major effective constituents of oral Gegen-Qinlian decoction in mice
por: Lu, Jing-Ze, et al.
Publicado: (2022)

Metformin and Gegen Qinlian Decoction boost islet α-cell proliferation of the STZ induced diabetic rats
por: Xu, Li, et al.
Publicado: (2022)

The potential effects and mechanisms of Gegen Qinlian Decoction in oxaliplatin-resistant colorectal cancer based on network pharmacology
por: Lin, Xiang, et al.
Publicado: (2022)

Gegen Qinlian decoction (GQD) inhibits ulcerative colitis by modulating ferroptosis-dependent pathway in mice and organoids
por: Wang, Xue, et al.
Publicado: (2023)

Gegen Qinlian Decoction Ameliorates Hyperuricemia-Induced Renal Tubular Injury via Blocking the Inflammatory Signaling Pathway
por: Wang, Xiao-Jun, et al.
Publicado: (2021)

Gegen-Qinlian decoction alleviates anxiety-like behaviors in methamphetamine-withdrawn mice by regulating Akkermansia and metabolism in the colon
por: Lu, Xue, et al.
Publicado: (2023)

Integrated Pharmacology Reveals the Molecular Mechanism of Gegen Qinlian Decoction Against Lipopolysaccharide-induced Acute Lung Injury
por: Li, Wei, et al.
Publicado: (2022)

Gegen Qinlian Decoction combined with Metformin for the treatment of patients with Type-2 Diabetes Mellitus: A retrospective observational study
por: Chen, Yingqi, et al.
Publicado: (2023)

Network Pharmacology-Based Strategy for Predicting Active Ingredients and Potential Targets of Gegen Qinlian Decoction for Rotavirus Enteritis
por: Zhong, Peicheng, et al.
Publicado: (2020)

Efficacy of herbal medicine (Gegen Qinlian Decoction) on ulcerative colitis: A systematic review of randomized controlled trials
por: Fan, Yuling, et al.
Publicado: (2019)

Focal Microscopy Observe the Mechanism of Gegen Qinlian Decoction Treating Type 2 Diabetic Nephropathy in Nude Mice
por: Zheng, Fei, et al.
Publicado: (2022)

Administration of modified Gegen Qinlian decoction for hemorrhagic chronic radiation proctitis: A case report and review of literature
por: Liu, Shao-Yong, et al.
Publicado: (2023)

Gegen Qinlian decoction enhances immunity and protects intestinal barrier function in colorectal cancer patients via gut microbiota
por: Li, Yang, et al.
Publicado: (2020)

Forkhead Transcription Factor FOXO1 Inhibits Angiogenesis in Gastric Cancer in Relation to SIRT1
por: Kim, Sue Youn, et al.
Publicado: (2016)

Herbal Formula Gegen-Qinlian Decoction for Type 2 Diabetes Mellitus: A Meta-Analysis of Randomized Controlled Trials
por: Ren, Lin, et al.
Publicado: (2020)

Exploration of the Mechanism of the Control of Coccidiosis in Chickens Based on Network Pharmacology and Molecular Docking With the Addition of Modified Gegen Qinlian Decoction
por: Peng, Xiaomin, et al.
Publicado: (2022)

Retracted: Focal Microscopy Observe the Mechanism of Gegen Qinlian Decoction Treating Type 2 Diabetic Nephropathy in Nude Mice
por: International, BioMed Research
Publicado: (2023)

Gegen Qinlian Decoction Coordinately Regulates PPARγ and PPARα to Improve Glucose and Lipid Homeostasis in Diabetic Rats and Insulin Resistance 3T3-L1 Adipocytes
por: Tu, Jun, et al.
Publicado: (2020)

Role of Forkhead Box Protein O1 (FoxO1) in Stroke: A Literature Review
por: Guo, Sichao, et al.
Publicado: (2022)

Forkhead Box Protein M1 Promotes Nasopharyngeal Carcinoma Cell Tumorigenesis Possibly via the Wnt/β-Catenin Signaling Pathway
por: Yu, Chao, et al.
Publicado: (2021)

Forkhead box protein O1 (FoxO1) /SERPINB1 ameliorates ROS production in diabetic nephropathy
por: Liang, Xiaoya, et al.
Publicado: (2020)

Compound to Extract to Formulation: a knowledge-transmitting approach for metabolites identification of Gegen-Qinlian Decoction, a traditional Chinese medicine formula
por: Qiao, Xue, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_skt7v929u0k3bicdv9p26assun