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Sonidegib, a Smoothened Inhibitor, Promotes Apoptosis and Suppresses Proliferation of Natural Killer/T-Cell Lymphoma

BACKGROUND: Dysregulation of the Hedgehog (Hh) pathway modulates various aspects of hematologic and solid tumors, but its effects in human Natural killer/T-cell lymphoma (NKTCL) are unclear. Moreover, no study has examined the consequences of pharmacologically inhibiting Hh signaling in NKTCL cell l...

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Detalles Bibliográficos
Autores principales:	Liu, Shengquan, Li, Chuntuan, Xin, Pengliang, Zheng, Yan, Peng, Qunyi, Xu, Yahong, Luo, Ying, Wu, Yishen, Zhu, Xiongpeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	International Scientific Literature, Inc. 2019
Materias:	Lab/In Vitro Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6873646/ https://www.ncbi.nlm.nih.gov/pubmed/31724562 http://dx.doi.org/10.12659/MSM.918812

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