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Bi- and tri-valent T cell engagers deplete tumour-associated macrophages in cancer patient samples

BACKGROUND: Tumour-associated macrophages (TAMs) are often implicated in cancer progression but can also exert anti-tumour activities. Selective eradication of cancer-promoting (M2-like) TAM subsets is a highly sought-after goal. Here, we have devised a novel strategy to achieve selective TAM deplet...

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Detalles Bibliográficos
Autores principales:	Scott, Eleanor M., Jacobus, Egon J., Lyons, Brian, Frost, Sally, Freedman, Joshua D., Dyer, Arthur, Khalique, Hena, Taverner, William K., Carr, Alison, Champion, Brian R., Fisher, Kerry D., Seymour, Len W., Duffy, Margaret R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6873687/ https://www.ncbi.nlm.nih.gov/pubmed/31753017 http://dx.doi.org/10.1186/s40425-019-0807-6

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