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Deep sequencing of hepatitis B surface antigen gene in the preserved umbilical cords in immunoprophylaxis failure against mother-to-child HBV transmission
BACKGROUND: Vaccine escape mutants (VEMs) are one of the causes of breakthrough infections in the mother-to-child transmission of hepatitis B virus (HBV). We hypothesized that VEMs existing as minor populations in the maternal blood are associated with breakthrough infections in children. We sought...
Autores principales: | Komatsu, Haruki, Inui, Ayano, Suzuki, Yasuto, Sugiyama, Masaya, Fujisawa, Tomoo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6873716/ https://www.ncbi.nlm.nih.gov/pubmed/31752732 http://dx.doi.org/10.1186/s12879-019-4624-9 |
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