Stress ulcer prophylaxis with proton pump inhibitors or histamine 2 receptor antagonists in critically ill adults - a meta-analysis of randomized controlled trials with trial sequential analysis

BACKGROUND: Proton pump inhibitors (PPI) and histamine 2 receptor antagonists (H2RA) have been widely used as stress ulcer prophylaxis (SUP) in critically ill patients, however, its efficacy and safety remain unclear. This study aimed to assess the effect of SUP on clinical outcomes in critically il...

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Detalles Bibliográficos
Autores principales: Zhou, Xiaoyang, Fang, Hanyuan, Xu, Jianfei, Chen, Peifu, Hu, Xujun, Chen, Bixin, Wang, Hua, Hu, Caibao, Xu, Zhaojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6873751/
https://www.ncbi.nlm.nih.gov/pubmed/31752703
http://dx.doi.org/10.1186/s12876-019-1105-y

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