Oriented attachment of V(NAR) proteins, via site-selective modification, on PLGA–PEG nanoparticles enhances nanoconjugate performance

Herein we report the construction of a nanoparticle-based drug delivery system which targets a key regulator in tumour angiogenesis. We exploit a Variable New Antigen Receptor (V(NAR)) domain, conjugated using site-specific chemistry, to direct poly lactic acid-co-glycolic acid–polyethylene glycol (...

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Detalles Bibliográficos
Autores principales: Nogueira, João C. F., Greene, Michelle K., Richards, Daniel A., Furby, Alexander O., Steven, John, Porter, Andrew, Barelle, Caroline, Scott, Christopher J., Chudasama, Vijay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6873773/
https://www.ncbi.nlm.nih.gov/pubmed/31204425
http://dx.doi.org/10.1039/c9cc02655j

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