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LFA-1 antagonist (BIRT377) similarly reverses peripheral neuropathic pain in male and female mice with underlying sex divergent peripheral immune proinflammatory phenotypes

AIM: The majority of preclinical studies investigating aberrant glial-neuroimmune actions underlying neuropathic pain have focused on male rodent models. Recently, studies have shown peripheral immune cells play a more prominent role than glial cells in mediating pathological pain in females. Here,...

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Detalles Bibliográficos
Autores principales:	Noor, Shahani, Sun, Melody S., Vanderwall, Arden G., Havard, Mara A., Sanchez, Jacob E., Harris, Nathan W., Nysus, Monique V., Norenberg, Jeffrey P., West, Harrison T., Wagner, Carsten R., Jantzie, Lauren L., Mellios, Nikolaos, Milligan, Erin D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6873931/ https://www.ncbi.nlm.nih.gov/pubmed/31763376 http://dx.doi.org/10.20517/2347-8659.2019.18

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