NEDD4 family ubiquitin ligases associate with LCMV Z’s PPXY domain and are required for virus budding, but not via direct ubiquitination of Z

Viral late domains are used by many viruses to recruit the cellular endosomal sorting complex required for transport (ESCRT) to mediate membrane scission during viral budding. Unlike the P(S/T)AP and YPX((1–3))L late domains, which interact directly with the ESCRT proteins Tsg101 and ALIX, the molec...

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Detalles Bibliográficos
Autores principales: Ziegler, Christopher M., Dang, Loan, Eisenhauer, Philip, Kelly, Jamie A., King, Benjamin R., Klaus, Joseph P., Manuelyan, Inessa, Mattice, Ethan B., Shirley, David J., Weir, Marion E., Bruce, Emily A., Ballif, Bryan A., Botten, Jason
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6874086/
https://www.ncbi.nlm.nih.gov/pubmed/31710650
http://dx.doi.org/10.1371/journal.ppat.1008100

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