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The Lineage Determining Factor GRHL2 Collaborates with FOXA1 to Establish a Targetable Pathway in Endocrine Therapy-Resistant Breast Cancer
Notwithstanding the positive clinical impact of endocrine therapies in estrogen receptor-alpha (ERα)-positive breast cancer, de novo and acquired resistance limits the therapeutic lifespan of existing drugs. Taking the position that resistance is nearly inevitable, we undertook a study to identify a...
Autores principales: | Cocce, Kimberly J., Jasper, Jeff S., Desautels, Taylor K., Everett, Logan, Wardell, Suzanne, Westerling, Thomas, Baldi, Robert, Wright, Tricia M., Tavares, Kendall, Yllanes, Alex, Bae, Yeeun, Blitzer, Jeremy T., Logsdon, Craig, Rakiec, Daniel P., Ruddy, David A., Jiang, Tiancong, Broadwater, Gloria, Hyslop, Terry, Hall, Allison, Laine, Muriel, Phung, Linda, Greene, Geoffrey L., Martin, Lesley-Ann, Pancholi, Sunil, Dowsett, Mitch, Detre, Simone, Marks, Jeffrey R., Crawford, Gregory E., Brown, Myles, Norris, John D., Chang, Ching-yi, McDonnell, Donald P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6874102/ https://www.ncbi.nlm.nih.gov/pubmed/31644911 http://dx.doi.org/10.1016/j.celrep.2019.09.032 |
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