Cargando…
eIF4E and 4EBP1 are prognostic markers of head and neck squamous cell carcinoma recurrence after definitive surgery and adjuvant radiotherapy
There is high risk of metastasis and recurrence in head and neck squamous cell carcinoma (HNSCC) patients, especially for patient who received definitive surgery and adjuvant radiotherapy. Aberrant activation of PI3K/AKT/mTOR signaling occurs in approximately 80% of HNSCC, which has been indicated t...
Autores principales: | Huang, Chung-I., Wang, Chih-Chun, Tai, Tzong-Shyuan, Hwang, Tzer-Zen, Yang, Chuan-Chien, Hsu, Chin-Mu, Su, Yu-Chieh |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6874317/ https://www.ncbi.nlm.nih.gov/pubmed/31756179 http://dx.doi.org/10.1371/journal.pone.0225537 |
Ejemplares similares
-
The eIF4EBP-eIF4E axis regulates CD4(+) T cell differentiation through modulation of T cell activation and metabolism
por: Istomine, Roman, et al.
Publicado: (2023) -
Metformin blocks MYC protein synthesis in colorectal cancer via mTOR‐4EBP‐eIF4E and MNK1‐eIF4G‐eIF4E signaling
por: Shen, Peng, et al.
Publicado: (2018) -
Synergistic activation of eIF4A by eIF4B and eIF4G
por: Nielsen, Klaus H., et al.
Publicado: (2011) -
BRDT is a novel regulator of eIF4EBP1 in renal cell carcinoma
por: Wan, Pei, et al.
Publicado: (2020) -
eIF4B, eIF4G and RNA regulate eIF4A activity in translation initiation by modulating the eIF4A conformational cycle
por: Harms, Ulf, et al.
Publicado: (2014)