Interleukin 21 (IL-21) regulates chronic allograft vasculopathy (CAV) in murine heart allograft rejection

IL-21 is the most recently discovered common gamma-chain cytokine that promotes persistent T-cell responses in chronic infections, autoimmunity and cancer. However, the therapeutic potential of inhibiting the IL-21-BATF signaling axis, particularly in transplant rejection, remains unclear. We used h...

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Detalles Bibliográficos
Autores principales: Khattar, Mithun, Baum, Caitlin E., Schroder, Paul, Breidenbach, Joshua D., Haller, Steven T., Chen, Wenhao, Stepkowski, Stanislaw
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6874341/
https://www.ncbi.nlm.nih.gov/pubmed/31756235
http://dx.doi.org/10.1371/journal.pone.0225624

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