Targeting the vascular-specific phosphatase PTPRB protects against retinal ganglion cell loss in a pre-clinical model of glaucoma

Elevated intraocular pressure (IOP) due to insufficient aqueous humor outflow through the trabecular meshwork and Schlemm’s canal (SC) is the most important risk factor for glaucoma, a leading cause of blindness worldwide. We previously reported loss of function mutations in the receptor tyrosine ki...

Descripción completa

Detalles Bibliográficos
Autores principales: Thomson, Benjamin R, Carota, Isabel A, Souma, Tomokazu, Soman, Saily, Vestweber, Dietmar, Quaggin, Susan E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6874417/
https://www.ncbi.nlm.nih.gov/pubmed/31621585
http://dx.doi.org/10.7554/eLife.48474

Ejemplares similares

Ejemplares similares