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Ser-Tyr and Asn-Ala, vasorelaxing dipeptides found by comprehensive screening, reduce blood pressure via different age-dependent mechanisms

To understand the changes in physiological responses due to aging, a number of bioactive probes based on different signal transduction pathways are necessary. In this study, we comprehensively and systematically investigated changes in blood vessel function with age using a 336-dipeptide library. In...

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Detalles Bibliográficos
Autores principales: Koyama, Daiki, Sun, Xinghui, Sasai, Masaki, Matsumura, Shigenobu, Inoue, Kazuo, Ohinata, Kousaku
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6874431/
https://www.ncbi.nlm.nih.gov/pubmed/31685714
http://dx.doi.org/10.18632/aging.102400