Cellular senescence induced by S100A9 in mesenchymal stromal cells through NLRP3 inflammasome activation

Bone marrow stromal cells from patients with myelodysplastic syndrome (MDS) display a senescence phenotype, but the underlying mechanism has not been elucidated. Pro-inflammatory signaling within the malignant clone and the bone marrow microenvironment has been identified as a key pathogenetic drive...

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Detalles Bibliográficos
Autores principales: Shi, Lei, Zhao, Youshan, Fei, Chengming, Guo, Juan, Jia, Yan, Wu, Dong, Wu, Lingyun, Chang, Chunkang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6874461/
https://www.ncbi.nlm.nih.gov/pubmed/31727865
http://dx.doi.org/10.18632/aging.102409

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6874461/
https://www.ncbi.nlm.nih.gov/pubmed/31727865
http://dx.doi.org/10.18632/aging.102409

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