Glycogen synthase kinase-3β suppresses the expression of protein phosphatase methylesterase-1 through β-catenin

Protein phosphatase 2A (PP2A) is the major tau phosphatase. Its activity toward tau is regulated by the methylation of PP2A catalytic subunit (PP2Ac) at Leu309. Protein phosphatase methylesterase-1 (PME-1) demethylates PP2Ac and suppresses its activity. We previously found that glycogen synthase kin...

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Detalles Bibliográficos
Autores principales: Jin, Nana, Shi, Ruirui, Jiang, Yanli, Chu, Dandan, Gong, Cheng-Xin, Iqbal, Khalid, Liu, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6874473/
https://www.ncbi.nlm.nih.gov/pubmed/31714894
http://dx.doi.org/10.18632/aging.102413

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6874473/
https://www.ncbi.nlm.nih.gov/pubmed/31714894
http://dx.doi.org/10.18632/aging.102413

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