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Glycogen synthase kinase-3β suppresses the expression of protein phosphatase methylesterase-1 through β-catenin

Protein phosphatase 2A (PP2A) is the major tau phosphatase. Its activity toward tau is regulated by the methylation of PP2A catalytic subunit (PP2Ac) at Leu309. Protein phosphatase methylesterase-1 (PME-1) demethylates PP2Ac and suppresses its activity. We previously found that glycogen synthase kin...

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Detalles Bibliográficos
Autores principales:	Jin, Nana, Shi, Ruirui, Jiang, Yanli, Chu, Dandan, Gong, Cheng-Xin, Iqbal, Khalid, Liu, Fei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals 2019
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6874473/ https://www.ncbi.nlm.nih.gov/pubmed/31714894 http://dx.doi.org/10.18632/aging.102413

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