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Rhabdo-immunodeficiency virus, a murine model of acute HIV-1 infection

Numerous challenges have impeded HIV-1 vaccine development. Among these is the lack of a convenient small animal model in which to study antibody elicitation and efficacy. We describe a chimeric Rhabdo-Immunodeficiency virus (RhIV) murine model that recapitulates key features of HIV-1 entry, tropism...

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Detalles Bibliográficos
Autores principales:	Liberatore, Rachel A, Mastrocola, Emily J, Cassella, Elena, Schmidt, Fabian, Willen, Jessie R, Voronin, Dennis, Zang, Trinity M, Hatziioannou, Theodora, Bieniasz, Paul D
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2019
Materias:	Microbiology and Infectious Disease
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6874478/ https://www.ncbi.nlm.nih.gov/pubmed/31644426 http://dx.doi.org/10.7554/eLife.49875

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