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Reciprocal Role Of DNA Methylation And Sp1 Binding In Ki-67 Gene Transcription

PURPOSE: DNA methylation plays major regulatory roles in gene transcription. Our previous studies confirmed that Ki-67 promoter is hypomethylated and Sp1 is a transcriptional activator of Ki-67 gene in cancer cells. However, whether Sp1-mediated transcriptional activation of Ki-67 is related to its...

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Detalles Bibliográficos
Autores principales:	Li, Lian-Tao, Wang, Xun, Zhu, Wen-Tao, Qian, Guo-Wei, Pei, Dong-Sheng, Zheng, Jun-Nian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2019
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6874502/ https://www.ncbi.nlm.nih.gov/pubmed/31819613 http://dx.doi.org/10.2147/CMAR.S213769

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