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Induction of HLA-A2 restricted CD8 T cell responses against ApoB100 peptides does not affect atherosclerosis in a humanized mouse model

Cardiovascular diseases form the most common cause of death worldwide, with atherosclerosis as main etiology. Atherosclerosis is marked by cholesterol rich lipoprotein deposition in the artery wall, evoking a pathogenic immune response. Characteristic for the disease is the pathogenic accumulation o...

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Detalles Bibliográficos
Autores principales: Schaftenaar, Frank H., Amersfoort, Jacob, Douna, Hidde, Kröner, Mara J., Foks, Amanda C., Bot, Ilze, Slütter, Bram A., van Puijvelde, Gijs H. M., Drijfhout, Jan W., Kuiper, Johan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6874568/
https://www.ncbi.nlm.nih.gov/pubmed/31757993
http://dx.doi.org/10.1038/s41598-019-53642-z