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Induction of HLA-A2 restricted CD8 T cell responses against ApoB100 peptides does not affect atherosclerosis in a humanized mouse model
Cardiovascular diseases form the most common cause of death worldwide, with atherosclerosis as main etiology. Atherosclerosis is marked by cholesterol rich lipoprotein deposition in the artery wall, evoking a pathogenic immune response. Characteristic for the disease is the pathogenic accumulation o...
Autores principales: | Schaftenaar, Frank H., Amersfoort, Jacob, Douna, Hidde, Kröner, Mara J., Foks, Amanda C., Bot, Ilze, Slütter, Bram A., van Puijvelde, Gijs H. M., Drijfhout, Jan W., Kuiper, Johan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6874568/ https://www.ncbi.nlm.nih.gov/pubmed/31757993 http://dx.doi.org/10.1038/s41598-019-53642-z |
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