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Lipid emulsion, but not propofol, induces skeletal muscle damage and lipid peroxidation

PURPOSE: Prolonged propofol infusion induces skeletal muscle damage. However, it is well known that the lipid emulsion that is the solvent of propofol causes various types of tissue damage via lipid peroxidation, and that propofol, conversely, has an anti-lipid peroxidative effect. The purpose of th...

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Detalles Bibliográficos
Autores principales: Chaki, Tomohiro, Hirata, Naoyuki, Yoshikawa, Yusuke, Tachibana, Shunsuke, Tokinaga, Yasuyuki, Yamakage, Michiaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Japan 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6874638/
https://www.ncbi.nlm.nih.gov/pubmed/31473808
http://dx.doi.org/10.1007/s00540-019-02676-8