Fabrication of Second Generation Smarter PLGA Based Nanocrystal Carriers for Improvement of Drug Delivery and Therapeutic Efficacy of Gliclazide in Type-2 Diabetes Rat Model

Drug delivery and therapeutic challenges of gliclazide, a BCS class II drug used in type 2 diabetes mellitus (T2DM) can be overcome by exploring smarter carriers of second-generation nanocrystals (SGNCs). A combined method of emulsion diffusion, high-pressure homogenization and solvent evaporation m...

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Detalles Bibliográficos
Autores principales: Panda, Bibhu Prasad, Krishnamoorthy, Rachna, Bhattamisra, Subrat Kumar, Shivashekaregowda, Naveen Kumar Hawala, Seng, Low Bin, Patnaik, Sujata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6874704/
https://www.ncbi.nlm.nih.gov/pubmed/31758056
http://dx.doi.org/10.1038/s41598-019-53996-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6874704/
https://www.ncbi.nlm.nih.gov/pubmed/31758056
http://dx.doi.org/10.1038/s41598-019-53996-4

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