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Tunnel engineering to accelerate product release for better biomass-degrading abilities in lignocellulolytic enzymes
BACKGROUND: For enzymes with buried active sites, transporting substrates/products ligands between active sites and bulk solvent via access tunnels is a key step in the catalytic cycle of these enzymes. Thus, tunnel engineering is becoming a powerful strategy to refine the catalytic properties of th...
Autores principales: | Lu, Zhenghui, Li, Xinzhi, Zhang, Rui, Yi, Li, Ma, Yanhe, Zhang, Guimin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6874815/ https://www.ncbi.nlm.nih.gov/pubmed/31768193 http://dx.doi.org/10.1186/s13068-019-1616-3 |
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