Cargando…

Midbrain microglia mediate a specific immunosuppressive response under inflammatory conditions

BACKGROUND: Inflammation is a critical process for the progression of neuronal death in neurodegenerative disorders. Microglia play a central role in neuroinflammation and may affect neuron vulnerability. Next generation sequencing has shown the molecular heterogeneity of microglial cells; however,...

Descripción completa

Detalles Bibliográficos
Autores principales:	Abellanas, Miguel Angel, Zamarbide, Marta, Basurco, Leyre, Luquin, Esther, Garcia-Granero, Marta, Clavero, Pedro, San Martin-Uriz, Patxi, Vilas, Amaia, Mengual, Elisa, Hervas-Stubbs, Sandra, Aymerich, Maria S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6874825/ https://www.ncbi.nlm.nih.gov/pubmed/31757220 http://dx.doi.org/10.1186/s12974-019-1628-8

Ejemplares similares

Microglia and astrocyte activation is region‐dependent in the α‐synuclein mouse model of Parkinson's disease
por: Basurco, Leyre, et al.
Publicado: (2022)

Stereological Estimates of Glutamatergic, GABAergic, and Cholinergic Neurons in the Pedunculopontine and Laterodorsal Tegmental Nuclei in the Rat
por: Luquin, Esther, et al.
Publicado: (2018)

IL-10 expression defines an immunosuppressive dendritic cell population induced by antitumor therapeutic vaccination
por: Llopiz, Diana, et al.
Publicado: (2016)

CB2 Receptors and Neuron–Glia Interactions Modulate Neurotoxicity Generated by MAGL Inhibition
por: Rojo-Bustamante, Estefania, et al.
Publicado: (2020)

Stereological estimations and neurochemical characterization of neurons expressing GABAA and GABAB receptors in the rat pedunculopontine and laterodorsal tegmental nuclei
por: Luquin, Esther, et al.
Publicado: (2021)

Gemcitabine-mediated depletion of immunosuppressive dendritic cells enhances the efficacy of therapeutic vaccination
por: Repáraz, David, et al.
Publicado: (2022)

Microglia integration into human midbrain organoids leads to increased neuronal maturation and functionality
por: Sabate‐Soler, Sonia, et al.
Publicado: (2022)

In vivo CRISPR-Cas9 inhibition of hepatic LDH as treatment of primary hyperoxaluria
por: Martinez-Turrillas, Rebeca, et al.
Publicado: (2022)

Astrocyte Hypertrophy and Microglia Activation in the Rat Auditory Midbrain Is Induced by Electrical Intracochlear Stimulation
por: Rosskothen-Kuhl, Nicole, et al.
Publicado: (2018)

Nickel-Resistance Determinants in Acidiphilium sp. PM Identified by Genome-Wide Functional Screening
por: San Martin-Uriz, Patxi, et al.
Publicado: (2014)

Genome-wide analysis of the H3K27me3 epigenome and transcriptome in Brassica rapa
por: Payá-Milans, Miriam, et al.
Publicado: (2019)

The Participation of Microglia in Neurogenesis: A Review
por: Pérez-Rodríguez, Diego R., et al.
Publicado: (2021)

40.2 MATERNAL IMMUNE ACTIVATION LEADS TO INCREASED LEVELS OF INFLAMMATORY CYTOKINES IN THE ABSENCE OF OVERT MICROGLIA ANOMALIES IN THE MIDBRAIN
por: Weber-Stadlbauer, Ulrike, et al.
Publicado: (2018)

Visualization of plasticity in fear-evoked calcium signals in midbrain dopamine neurons
por: Gore, Bryan B., et al.
Publicado: (2014)

Deconvolution of the hematopoietic stem cell microenvironment reveals a high degree of specialization and conservation
por: Ye, Jin, et al.
Publicado: (2022)

Transposase interaction with the β sliding clamp: effects on insertion sequence proliferation and transposition rate
por: Díaz-Maldonado, Héctor, et al.
Publicado: (2015)

Midbrain cysticercal cyst
por: Shukla, Dhaval
Publicado: (2012)

A Medley of Midbrain Maladies: A Brief Review of Midbrain Anatomy and Syndromology for Radiologists
por: Ruchalski, Kathleen, et al.
Publicado: (2012)

Microglia promote glioblastoma via mTOR‐mediated immunosuppression of the tumour microenvironment
por: Dumas, Anaelle A, et al.
Publicado: (2020)

Neurophilic Descending Migration of Dorsal Midbrain Neurons Into the Hindbrain
por: García-Peña, Claudia M., et al.
Publicado: (2018)

Developmental disorders of the midbrain and hindbrain
por: Barkovich, A. James
Publicado: (2012)

Narcolepsy in midbrain structural lesion
por: Renna, Rosaria, et al.
Publicado: (2016)

The clinical variability of midbrain lesions
por: Federico, Pacei
Publicado: (2017)

Microbial mediated formation of Fe-carbonate minerals under extreme acidic conditions
por: Sánchez-Román, Mónica, et al.
Publicado: (2014)

P05.01. Case Report: Dysconjugate Gaze in a Patient With Graves' Orbitopathy
por: Taw, Malcolm, et al.
Publicado: (2013)

Reduced microglia activity in patients with long-term immunosuppressive therapy after liver transplantation
por: Dirks, Meike, et al.
Publicado: (2021)

Characterization of complete lncRNAs transcriptome reveals the functional and clinical impact of lncRNAs in multiple myeloma
por: Carrasco-Leon, Arantxa, et al.
Publicado: (2021)

Cysticercosis of midbrain presenting with fluctuating ptosis
por: Netravathi, M., et al.
Publicado: (2011)

Reliability in the Identification of Midbrain Dopamine Neurons
por: Margolis, Elyssa B., et al.
Publicado: (2010)

Cortical modulation of auditory processing in the midbrain
por: Bajo, Victoria M., et al.
Publicado: (2013)

Spatial frequency sensitivity in macaque midbrain
por: Chen, Chih-Yang, et al.
Publicado: (2018)

Background firing in the auditory midbrain of the frog
por: Bibikov, N.G.
Publicado: (2017)

Acquisition of the Midbrain Dopaminergic Neuronal Identity
por: Mesman, Simone, et al.
Publicado: (2020)

Distribution of Midbrain Cholinergic Axons in the Thalamus
por: Huerta-Ocampo, Icnelia, et al.
Publicado: (2020)

Transcriptomic encoding of sensorimotor transformation in the midbrain
por: Xie, Zhiyong, et al.
Publicado: (2021)

Multipartner Symbiosis across Biological Domains: Looking at the Eukaryotic Associations from a Microbial Perspective
por: Turon, Marta, et al.
Publicado: (2019)

How to reprogram microglia toward beneficial functions
por: Fumagalli, Marta, et al.
Publicado: (2018)

Pleiotrophin regulates microglia-mediated neuroinflammation
por: Fernández-Calle, Rosalía, et al.
Publicado: (2017)

Exploring the Disease-Associated Microglia State in Amyotrophic Lateral Sclerosis
por: Jauregui, Carlota, et al.
Publicado: (2023)

Functional and transcriptomic analysis of extracellular vesicles identifies calprotectin as a new prognostic marker in peripheral arterial disease (PAD)
por: Saenz-Pipaon, Goren, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_gpksam71c66tcpvk4qopdpelnf