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Ethanol Exposure Induces Microglia Activation and Neuroinflammation through TLR4 Activation and SENP6 Modulation in the Adolescent Rat Hippocampus

The ethanol-induced toll-like receptor 4 (TLR4) signal activation of microglia and neuroinflammation are observed in both adolescent and adult rat brains, but the regulatory mechanisms of some TLR4 signaling-related factors in this process are still unclear. SUMO-specific protease 6 (SENP6) inhibits...

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Detalles Bibliográficos
Autores principales: Li, Qing, Liu, Dexiang, Pan, Fang, Ho, Cyrus S. H., Ho, Roger C. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6874951/
https://www.ncbi.nlm.nih.gov/pubmed/31781182
http://dx.doi.org/10.1155/2019/1648736