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Dihydroartemisinin Protects against Dextran Sulfate Sodium-Induced Colitis in Mice through Inhibiting the PI3K/AKT and NF-κB Signaling Pathways

Ulcerative colitis is a common inflammatory bowel disease, and the activation of thePI3K/AKT and NF-κB signaling pathways plays a pivotal role in its pathogenesis. Dihydroartemisinin (DHA) is a widely used antimalarial drug and has shown anticancer effect partially through inhibiting the activation...

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Detalles Bibliográficos
Autores principales: Li, Ning, Sun, Wenjing, Zhou, Xin, Gong, Hao, Chen, Yuqing, Chen, Dongfeng, Xiang, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6875009/
https://www.ncbi.nlm.nih.gov/pubmed/31781591
http://dx.doi.org/10.1155/2019/1415809

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