Update on Myopia Risk Factors and Microenvironmental Changes

The focus of this update is to emphasize the recent advances in the pathogenesis and various molecular key approaches associated with myopia in order to reveal new potential therapeutic targets. We review the current evidence for its complex genetics and evaluate the known or candidate genes and loc...

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Detalles Bibliográficos
Autores principales: Coviltir, Valeria, Burcel, Miruna, Cherecheanu, Alina Popa, Ionescu, Catalina, Dascalescu, Dana, Potop, Vasile, Burcea, Marian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6875023/
https://www.ncbi.nlm.nih.gov/pubmed/31781378
http://dx.doi.org/10.1155/2019/4960852
Descripción
Sumario:The focus of this update is to emphasize the recent advances in the pathogenesis and various molecular key approaches associated with myopia in order to reveal new potential therapeutic targets. We review the current evidence for its complex genetics and evaluate the known or candidate genes and loci. In addition, we discuss recent investigations regarding the role of environmental factors. This paper also covers current research aimed at elucidating the signaling pathways involved in the pathogenesis of myopia.

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