Update on Myopia Risk Factors and Microenvironmental Changes

The focus of this update is to emphasize the recent advances in the pathogenesis and various molecular key approaches associated with myopia in order to reveal new potential therapeutic targets. We review the current evidence for its complex genetics and evaluate the known or candidate genes and loc...

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Detalles Bibliográficos
Autores principales: Coviltir, Valeria, Burcel, Miruna, Cherecheanu, Alina Popa, Ionescu, Catalina, Dascalescu, Dana, Potop, Vasile, Burcea, Marian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6875023/
https://www.ncbi.nlm.nih.gov/pubmed/31781378
http://dx.doi.org/10.1155/2019/4960852
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author Coviltir, Valeria
Burcel, Miruna
Cherecheanu, Alina Popa
Ionescu, Catalina
Dascalescu, Dana
Potop, Vasile
Burcea, Marian
author_facet Coviltir, Valeria
Burcel, Miruna
Cherecheanu, Alina Popa
Ionescu, Catalina
Dascalescu, Dana
Potop, Vasile
Burcea, Marian
author_sort Coviltir, Valeria
collection PubMed
description The focus of this update is to emphasize the recent advances in the pathogenesis and various molecular key approaches associated with myopia in order to reveal new potential therapeutic targets. We review the current evidence for its complex genetics and evaluate the known or candidate genes and loci. In addition, we discuss recent investigations regarding the role of environmental factors. This paper also covers current research aimed at elucidating the signaling pathways involved in the pathogenesis of myopia.
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spelling pubmed-68750232019-11-28 Update on Myopia Risk Factors and Microenvironmental Changes Coviltir, Valeria Burcel, Miruna Cherecheanu, Alina Popa Ionescu, Catalina Dascalescu, Dana Potop, Vasile Burcea, Marian J Ophthalmol Review Article The focus of this update is to emphasize the recent advances in the pathogenesis and various molecular key approaches associated with myopia in order to reveal new potential therapeutic targets. We review the current evidence for its complex genetics and evaluate the known or candidate genes and loci. In addition, we discuss recent investigations regarding the role of environmental factors. This paper also covers current research aimed at elucidating the signaling pathways involved in the pathogenesis of myopia. Hindawi 2019-10-31 /pmc/articles/PMC6875023/ /pubmed/31781378 http://dx.doi.org/10.1155/2019/4960852 Text en Copyright © 2019 Valeria Coviltir et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Coviltir, Valeria
Burcel, Miruna
Cherecheanu, Alina Popa
Ionescu, Catalina
Dascalescu, Dana
Potop, Vasile
Burcea, Marian
Update on Myopia Risk Factors and Microenvironmental Changes
title Update on Myopia Risk Factors and Microenvironmental Changes
title_full Update on Myopia Risk Factors and Microenvironmental Changes
title_fullStr Update on Myopia Risk Factors and Microenvironmental Changes
title_full_unstemmed Update on Myopia Risk Factors and Microenvironmental Changes
title_short Update on Myopia Risk Factors and Microenvironmental Changes
title_sort update on myopia risk factors and microenvironmental changes
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6875023/
https://www.ncbi.nlm.nih.gov/pubmed/31781378
http://dx.doi.org/10.1155/2019/4960852
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