Rosiglitazone Suppresses Calcium Oxalate Crystal Binding and Oxalate-Induced Oxidative Stress in Renal Epithelial Cells by Promoting PPAR-γ Activation and Subsequent Regulation of TGF-β1 and HGF Expression

Peroxisome proliferator-activated receptor- (PPAR-) γ is a ligand-dependent transcription factor, and it has become evident that PPAR-γ agonists have renoprotective effects, but their influence and mechanism during the development of calcium oxalate (CaOx) nephrolithiasis remain unknown. Rosiglitazo...

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Detalles Bibliográficos
Autores principales: Liu, Ya-Dong, Yu, Shi-Liang, Wang, Rui, Liu, Jian-Nan, Jin, Yin-Shan, Li, Yi-Fu, An, Rui-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6875173/
https://www.ncbi.nlm.nih.gov/pubmed/31781338
http://dx.doi.org/10.1155/2019/4826525

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