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Isolated Small Finger Distal Interphalangeal Joint Dupuytren's Contracture

Dupuytren's contracture is a disease involving abnormal myofibroblast proliferation and collagen deposition leading to the formation of pathologic cords in the hand. Given that Dupuytren's contractures rarely extend to the distal interphalangeal joint (DIP), affecting only 5% of patients,...

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Autores principales: Mehdi, Syed K., King, John D., Keshtvarz, Sara, Kamineni, Srinath, Dhawan, Vikas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6875190/
https://www.ncbi.nlm.nih.gov/pubmed/31781455
http://dx.doi.org/10.1155/2019/7183739
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author Mehdi, Syed K.
King, John D.
Keshtvarz, Sara
Kamineni, Srinath
Dhawan, Vikas
author_facet Mehdi, Syed K.
King, John D.
Keshtvarz, Sara
Kamineni, Srinath
Dhawan, Vikas
author_sort Mehdi, Syed K.
collection PubMed
description Dupuytren's contracture is a disease involving abnormal myofibroblast proliferation and collagen deposition leading to the formation of pathologic cords in the hand. Given that Dupuytren's contractures rarely extend to the distal interphalangeal joint (DIP), affecting only 5% of patients, there are few cases reported in the literature. Collagenase injection is a frequently used option for minimally invasive treatment of Dupuytren's disease with greater than a 20-degree joint contracture. Unfortunately, there is limited research on the effectiveness of these injections in isolated DIP joint deformities. We present a case of a 61-year-old right hand-dominant male with a 2-year history of isolated right small finger Dupuytren's contracture at the DIP joint who achieved significant improvement after collagenase injection.
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spelling pubmed-68751902019-11-28 Isolated Small Finger Distal Interphalangeal Joint Dupuytren's Contracture Mehdi, Syed K. King, John D. Keshtvarz, Sara Kamineni, Srinath Dhawan, Vikas Case Rep Orthop Case Report Dupuytren's contracture is a disease involving abnormal myofibroblast proliferation and collagen deposition leading to the formation of pathologic cords in the hand. Given that Dupuytren's contractures rarely extend to the distal interphalangeal joint (DIP), affecting only 5% of patients, there are few cases reported in the literature. Collagenase injection is a frequently used option for minimally invasive treatment of Dupuytren's disease with greater than a 20-degree joint contracture. Unfortunately, there is limited research on the effectiveness of these injections in isolated DIP joint deformities. We present a case of a 61-year-old right hand-dominant male with a 2-year history of isolated right small finger Dupuytren's contracture at the DIP joint who achieved significant improvement after collagenase injection. Hindawi 2019-11-04 /pmc/articles/PMC6875190/ /pubmed/31781455 http://dx.doi.org/10.1155/2019/7183739 Text en Copyright © 2019 Syed K. Mehdi et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Mehdi, Syed K.
King, John D.
Keshtvarz, Sara
Kamineni, Srinath
Dhawan, Vikas
Isolated Small Finger Distal Interphalangeal Joint Dupuytren's Contracture
title Isolated Small Finger Distal Interphalangeal Joint Dupuytren's Contracture
title_full Isolated Small Finger Distal Interphalangeal Joint Dupuytren's Contracture
title_fullStr Isolated Small Finger Distal Interphalangeal Joint Dupuytren's Contracture
title_full_unstemmed Isolated Small Finger Distal Interphalangeal Joint Dupuytren's Contracture
title_short Isolated Small Finger Distal Interphalangeal Joint Dupuytren's Contracture
title_sort isolated small finger distal interphalangeal joint dupuytren's contracture
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6875190/
https://www.ncbi.nlm.nih.gov/pubmed/31781455
http://dx.doi.org/10.1155/2019/7183739
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