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Metformin Activates the Protective Effects of the AMPK Pathway in Acute Lung Injury Caused by Paraquat Poisoning
OBJECTIVE: To observe whether metformin (MET) plays a protective role in acute lung injury (ALI) induced by paraquat (PQ) poisoning in rats by activating the AMPK/NF-κB signaling pathway. METHODS: PQ exposure was used to construct a rat model of ALI and a model of acute type II alveolar epithelial c...
Autores principales: | Wu, Liaozhang, Cen, Yifang, Feng, Menglong, Zhou, Yanna, Tang, Hui, Liao, Xueli, Wang, Yanze, Wang, Min, Zhou, Manhong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6875205/ https://www.ncbi.nlm.nih.gov/pubmed/31781324 http://dx.doi.org/10.1155/2019/1709718 |
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