Cargando…

Intra-Bone Marrow Administration of Mesenchymal Stem/Stromal Cells Is a Promising Approach for Treating Osteoporosis

Mesenchymal stem/stromal cells (MSCs) are known to be useful for treating local bone diseases. However, it is not known if MSCs are effective for treating systemic bone diseases, as the risk for mortality following intravenous MSC administration has hindered research progress. In this study, we comp...

Descripción completa

Detalles Bibliográficos
Autores principales:	Agata, Hideki, Sumita, Yoshinori, Hidaka, Tatsuro, Iwatake, Mayumi, Kagami, Hideaki, Asahina, Izumi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6875206/ https://www.ncbi.nlm.nih.gov/pubmed/31781240 http://dx.doi.org/10.1155/2019/4214281

Ejemplares similares

Clinical Outcome and 8-Year Follow-Up of Alveolar Bone Tissue Engineering for Severely Atrophic Alveolar Bone Using Autologous Bone Marrow Stromal Cells with Platelet-Rich Plasma and β-Tricalcium Phosphate Granules
por: Asahina, Izumi, et al.
Publicado: (2021)

A Clinical Study of Alveolar Bone Tissue Engineering Using Autologous Bone Marrow Stromal Cells: Effect of Optimized Cell-Processing Protocol on Efficacy
por: Kagami, Hideaki, et al.
Publicado: (2022)

Gene-activated matrix harboring a miR20a-expressing plasmid promotes rat cranial bone augmentation
por: Shido, Rena, et al.
Publicado: (2021)

Gene-Activated Matrix with Self-Assembly Anionic Nano-Device Containing Plasmid DNAs for Rat Cranial Bone Augmentation
por: Hara, Masahito, et al.
Publicado: (2021)

Immunomodulatory Macrophages Enable E-MNC Therapy for Radiation-Induced Salivary Gland Hypofunction
por: Honma, Ryo, et al.
Publicado: (2023)

Transient Exposure to Hypoxic and Anoxic Oxygen Concentrations Promotes Either Osteogenic or Ligamentogenic Characteristics of PDL Cells
por: Kawasaki, Takako, et al.
Publicado: (2015)

Effective-mononuclear cell (E-MNC) therapy alleviates salivary gland damage by suppressing lymphocyte infiltration in Sjögren-like disease
por: Hasegawa, Kayo, et al.
Publicado: (2023)

Gene-Activated Matrix Comprised of Atelocollagen and Plasmid DNA Encoding BMP4 or Runx2 Promotes Rat Cranial Bone Augmentation
por: Umebayashi, Mayumi, et al.
Publicado: (2015)

Bone marrow concentrate promotes bone regeneration with a suboptimal-dose of rhBMP-2
por: Egashira, Kazuhiro, et al.
Publicado: (2018)

In Vivo Comparison of the Bone Regeneration Capability of Human Bone Marrow Concentrates vs. Platelet-Rich Plasma
por: Zhong, Weijian, et al.
Publicado: (2012)

Anti-inflammatory and vasculogenic conditioning of peripheral blood mononuclear cells reinforces their therapeutic potential for radiation-injured salivary glands
por: I., Takashi, et al.
Publicado: (2019)

Phase 1 clinical study of cell therapy with effective-mononuclear cells (E-MNC) for radiogenic xerostomia (first-in-human study) (FIH study on E-MNC therapy for radiogenic xerostomia)
por: Sumita, Yoshinori, et al.
Publicado: (2020)

Systemic administration of quality- and quantity-controlled PBMNCs reduces bisphosphonate-related osteonecrosis of jaw-like lesions in mice
por: Kuroshima, Shinichiro, et al.
Publicado: (2019)

CXCL12 and osteopontin from bone marrow-derived mesenchymal stromal cells improve muscle regeneration
por: Maeda, Yasushi, et al.
Publicado: (2017)

Age-related Changes in Bone Marrow Mesenchymal Stromal Cells: A Potential Impact on Osteoporosis and Osteoarthritis Development
por: Ganguly, Payal, et al.
Publicado: (2017)

Do not keep it simple: recent advances in the generation of complex organoids
por: Wörsdörfer, Philipp, et al.
Publicado: (2020)

First-in-Human Study to Investigate the Safety Assessment of Peri-Implant Soft Tissue Regeneration with Micronized-Gingival Connective Tissue: A Pilot Case Series Study
por: I, Takashi, et al.
Publicado: (2023)

A Prospective Study of the Assessment of the Efficacy of a Biodegradable Poly(l-lactic acid/ε-caprolactone) Membrane for Guided Bone Regeneration
por: Shido, Rena, et al.
Publicado: (2023)

Senile Osteoporosis: The Involvement of Differentiation and Senescence of Bone Marrow Stromal Cells
por: Qadir, Abdul, et al.
Publicado: (2020)

Resident CD34-positive cells contribute to peri-endothelial cells and vascular morphogenesis in salivary gland after irradiation
por: I, Takashi, et al.
Publicado: (2020)

Increased In Vitro Intercellular Barrier Function of Lung Epithelial Cells Using Adipose-Derived Mesenchymal Stem/Stromal Cells
por: Ishii, Mitsutoshi, et al.
Publicado: (2021)

Clinical Safety Assessment of Autologous Freeze-Drying Platelet-Rich Plasma for Bone Regeneration in Maxillary Sinus Floor Augmentation: A Pilot Study
por: Koga, Takamitsu, et al.
Publicado: (2021)

Legumain Regulates Differentiation Fate of Human Bone Marrow Stromal Cells and Is Altered in Postmenopausal Osteoporosis
por: Jafari, Abbas, et al.
Publicado: (2017)

Cryopreserved Spontaneous Spheroids from Compact Bone-Derived Mesenchymal Stromal Cells for Bone Tissue Engineering
por: Dong, Hongwei, et al.
Publicado: (2021)

Timing of Mesenchymal Stromal Cell Therapy Defines its Immunosuppressive Effects in a Rat Lung Transplantation Model
por: Tanoue, Yukinori, et al.
Publicado: (2023)

Bone Regeneration Using Dentin Matrix Depends on the Degree of Demineralization and Particle Size
por: Koga, Takamitsu, et al.
Publicado: (2016)

Intra-pancreatic tissue-derived mesenchymal stromal cells: a promising therapeutic potential with anti-inflammatory and pro-angiogenic profiles
por: Khiatah, Bashar, et al.
Publicado: (2019)

Circular RNAs: Promising Targets in Osteoporosis
por: Moura, Sara Reis, et al.
Publicado: (2023)

Glucocorticoid-Induced Osteoporosis – A Disorder of Mesenchymal Stromal Cells?
por: Hardy, Rowan, et al.
Publicado: (2011)

Mesenchymal stem/stromal cells-derived exosomes for osteoporosis treatment
por: Huo, Kai-Lun, et al.
Publicado: (2023)

Morphology-Based Prediction of Osteogenic Differentiation Potential of Human Mesenchymal Stem Cells
por: Matsuoka, Fumiko, et al.
Publicado: (2013)

Mesenchymal stromal cells: promising treatment for liver cirrhosis
por: Yao, Lichao, et al.
Publicado: (2022)

P1260: BIODISTRIBUTION OF LABELED AUTOLOGOUS AND ALLOGENEIC BONE MARROW MESENCHYMAL STROMAL CELLS IN RABBITS AFTER INTRAVENOUS ADMINISTRATION
por: Pestrikova, Anastasiya, et al.
Publicado: (2023)

Characterization of Time-Course Morphological Features for Efficient Prediction of Osteogenic Potential in Human Mesenchymal Stem Cells
por: Matsuoka, Fumiko, et al.
Publicado: (2014)

Intra-Bone Marrow Transplantation of Endosteal Bone Marrow Cells Facilitates Allogeneic Hematopoietic and Stromal Cells Engraftment Dependent on Early Expression of CXCL-12
por: Chen, Chen, et al.
Publicado: (2015)

Mesenchymal stromal cells. Nurse-like cells reside in the synovial tissue and bone marrow in rheumatoid arthritis
por: Ochi, Takahiro, et al.
Publicado: (2007)

Comparing the immunosuppressive potency of naïve marrow stromal cells and Notch-transfected marrow stromal cells
por: Dao, Mo A, et al.
Publicado: (2011)

Comparing the angiogenic potency of naïve marrow stromal cells and Notch-transfected marrow stromal cells
por: Dao, Mo, et al.
Publicado: (2013)

In Vitro Screening Studies on Eight Commercial Essential Oils-Derived Compounds to Identify Promising Natural Agents for the Prevention of Osteoporosis
por: Trzaskowska, Marta, et al.
Publicado: (2023)

Qualitative Aspects of Bone Marrow Adiposity in Osteoporosis
por: Pino, Ana María, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_meemans0f2q0rkjthbchd85nit