Effects of Anti-Cytokine Antibodies on Gut Barrier Function

Anti-cytokine antibodies are used in treating chronic inflammatory diseases and autoimmune diseases such as inflammatory bowel disease and rheumatic diseases. Patients with these diseases often have a compromised gut barrier function, suggesting that anti-cytokine antibodies may contribute to the re...

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Detalles Bibliográficos
Autores principales: Liu, Fang, Lee, Seul A., Riordan, Stephen M., Zhang, Li, Zhu, Lixin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6875247/
https://www.ncbi.nlm.nih.gov/pubmed/31780866
http://dx.doi.org/10.1155/2019/7028253
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author Liu, Fang
Lee, Seul A.
Riordan, Stephen M.
Zhang, Li
Zhu, Lixin
author_facet Liu, Fang
Lee, Seul A.
Riordan, Stephen M.
Zhang, Li
Zhu, Lixin
author_sort Liu, Fang
collection PubMed
description Anti-cytokine antibodies are used in treating chronic inflammatory diseases and autoimmune diseases such as inflammatory bowel disease and rheumatic diseases. Patients with these diseases often have a compromised gut barrier function, suggesting that anti-cytokine antibodies may contribute to the re-establishment of gut barrier integrity, in addition to their immunomodulatory effects. This paper reviews the effects of anti-cytokine antibodies on gut barrier function and their mechanisms.
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spelling pubmed-68752472019-11-28 Effects of Anti-Cytokine Antibodies on Gut Barrier Function Liu, Fang Lee, Seul A. Riordan, Stephen M. Zhang, Li Zhu, Lixin Mediators Inflamm Review Article Anti-cytokine antibodies are used in treating chronic inflammatory diseases and autoimmune diseases such as inflammatory bowel disease and rheumatic diseases. Patients with these diseases often have a compromised gut barrier function, suggesting that anti-cytokine antibodies may contribute to the re-establishment of gut barrier integrity, in addition to their immunomodulatory effects. This paper reviews the effects of anti-cytokine antibodies on gut barrier function and their mechanisms. Hindawi 2019-11-12 /pmc/articles/PMC6875247/ /pubmed/31780866 http://dx.doi.org/10.1155/2019/7028253 Text en Copyright © 2019 Fang Liu et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Liu, Fang
Lee, Seul A.
Riordan, Stephen M.
Zhang, Li
Zhu, Lixin
Effects of Anti-Cytokine Antibodies on Gut Barrier Function
title Effects of Anti-Cytokine Antibodies on Gut Barrier Function
title_full Effects of Anti-Cytokine Antibodies on Gut Barrier Function
title_fullStr Effects of Anti-Cytokine Antibodies on Gut Barrier Function
title_full_unstemmed Effects of Anti-Cytokine Antibodies on Gut Barrier Function
title_short Effects of Anti-Cytokine Antibodies on Gut Barrier Function
title_sort effects of anti-cytokine antibodies on gut barrier function
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6875247/
https://www.ncbi.nlm.nih.gov/pubmed/31780866
http://dx.doi.org/10.1155/2019/7028253
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