Stress-Coping Humoral Glycolipids Produced by Mice Given Controlled Bathing Treatments

Mammalians have recognition-behavioral stress-coping neuronal module system followed by some humoral glycolipids. A sulfated Galbeta1-4GlcNAc-lipid promotes the serotonergic module regulating the emotional behaviors for not-wasting the physical strength; GalNAcalpha1-3GalNAc-lipid promotes the adrenergic module inducing the behaviors escaping from the uneasy situation, and sulfated Fucalpha1-2Gal-lipid protects the cholinergic module keeping the stressor-memory from the ischemia-stress. Mouse given bathing recognizes the stressors to be coped with in the treatment. We previously observed mouse given CO(2)-microbubble-bathing increased the behavior escaping from the bathing situation. Mouse given CO(2)-microbubble-bathing would recognize the other stressors to be coped with in the treatment. We examined stress-coping glycolipids produced by mice given controlled bathing treatments, and got the following results. A sulfated Galbeta1-4GlcNAc-lipid production was increased by the acidic bathing condition and the dissolved CO(2), GalNAcalpha1-3GalNAc-lipid production was increased by the dissolved CO(2), and sulfated Fucalpha1-2Gal-lipid production was increased by the acidic bathing condition. We understood the mice treated with CO(2)-microbubble-bathing would recognize the acidic bathing condition and the dissolved CO(2), but not the microbubble, as the other stressors to be coped.