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IL-6 Negatively Regulates IL-22Rα Expression on Epidermal Keratinocytes: Implications for Irritant Contact Dermatitis

Irritant Contact Dermatitis (ICD) is characterized by epidermal hyperplasia and inflammatory cytokine release. IL-6 has been shown to be involved in the pathogenesis of ICD; however, the involvement of the IL-22/IL-22Rα axis and its relation to IL-6 in the inflammatory response following irritant ex...

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Detalles Bibliográficos
Autores principales: Frempah, Benjamin, Luckett-Chastain, Lerin R., Gallucci, Randle M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6875369/
https://www.ncbi.nlm.nih.gov/pubmed/31781680
http://dx.doi.org/10.1155/2019/6276254