Cargando…
Methane Alleviates Acetaminophen-Induced Liver Injury by Inhibiting Inflammation, Oxidative Stress, Endoplasmic Reticulum Stress, and Apoptosis through the Nrf2/HO-1/NQO1 Signaling Pathway
Acetaminophen- (APAP-) induced hepatic injury is an important clinical challenge. Oxidative stress, inflammation, apoptosis, and endoplasmic reticulum stress (ERS) contribute to the pathogenesis. Methane has potential anti-inflammatory, antioxidant, and antiapoptotic properties. This project was aim...
Autores principales: | Feng, Yang, Cui, Ruixia, Li, Zeyu, Zhang, Xia, Jia, Yifan, Zhang, Xing, Shi, Jinghong, Qu, Kai, Liu, Chang, Zhang, Jingyao |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6875424/ https://www.ncbi.nlm.nih.gov/pubmed/31781345 http://dx.doi.org/10.1155/2019/7067619 |
Ejemplares similares
-
Methane-Rich Saline Ameliorates Sepsis-Induced Acute Kidney Injury through Anti-Inflammation, Antioxidative, and Antiapoptosis Effects by Regulating Endoplasmic Reticulum Stress
por: Jia, Yifan, et al.
Publicado: (2018) -
Cardamom Extract Alleviates the Oxidative Stress, Inflammation and Apoptosis Induced during Acetaminophen-Induced Hepatic Toxicity via Modulating Nrf2/HO-1/NQO-1 Pathway
por: Alkhalifah, Essraa A. R., et al.
Publicado: (2022) -
Sulforaphane Delays Intervertebral Disc Degeneration by Alleviating Endoplasmic Reticulum Stress in Nucleus Pulposus Cells via Activating Nrf-2/HO-1
por: Lu, Xiao, et al.
Publicado: (2023) -
Penehyclidine Hydrochloride Pretreatment Ameliorates Rhabdomyolysis-Induced AKI by Activating the Nrf2/HO-1 Pathway and Allevi-ating Endoplasmic Reticulum Stress in Rats
por: Zhao, Wei, et al.
Publicado: (2016) -
CO/HO-1 Induces NQO-1 Expression via Nrf2 Activation
por: Kim, Hyo Jeong, et al.
Publicado: (2011)