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Twenty-year Follow-up of the First Bilateral Living-donor Lobar Lung Transplantation in Japan

Patients with end-stage lung disease can undergo living-donor lobar lung transplantation (LDLLT), with survival rates improving every year. We herein report the 20-year follow-up findings of the first patient who underwent LDLLT in Japan. A 24-year-old woman with primary ciliary dyskinesia became ve...

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Detalles Bibliográficos
Autores principales: Komatsu, Masamichi, Yamamoto, Hiroshi, Shomura, Toshitaka, Sonehara, Kei, Ichiyama, Takashi, Urushihata, Kazuhisa, Ushiki, Atsuhito, Yasuo, Masanori, Wakamatsu, Toshihide, Sugimoto, Seiichiro, Oto, Takahiro, Date, Hiroshi, Koizumi, Tomonobu, Hanaoka, Masayuki, Kubo, Keishi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6875472/
https://www.ncbi.nlm.nih.gov/pubmed/31292405
http://dx.doi.org/10.2169/internalmedicine.3160-19
Descripción
Sumario:Patients with end-stage lung disease can undergo living-donor lobar lung transplantation (LDLLT), with survival rates improving every year. We herein report the 20-year follow-up findings of the first patient who underwent LDLLT in Japan. A 24-year-old woman with primary ciliary dyskinesia became ventilator-dependent after severe respiratory failure and right-sided heart failure following repeated respiratory infections. In 1998, she underwent LDLLT and received her sister’s right lower lobe and her mother’s left lower lobe. Although the patient required 21 hospitalizations and developed unilateral bronchiolitis obliterans syndrome, she is in good physical condition and lives without restriction at 20 years after undergoing LDLLT.