Alcohol-Related Thiamine Deficiency: Impact on Cognitive and Memory Functioning

Chronic alcohol abuse is associated with several neurological disorders, including Wernicke-Korsakoff syndrome (WKS). Deficiency of thiamine—a vitamin essential for the metabolism and function of brain cells—is thought to be one factor contributing to the cognitive deficits and brain pathology chara...

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Detalles Bibliográficos
Autor principal: Langlais, Philip J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Institute on Alcohol Abuse and Alcoholism 1995
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6875731/
https://www.ncbi.nlm.nih.gov/pubmed/31798071
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author Langlais, Philip J.
author_facet Langlais, Philip J.
author_sort Langlais, Philip J.
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description Chronic alcohol abuse is associated with several neurological disorders, including Wernicke-Korsakoff syndrome (WKS). Deficiency of thiamine—a vitamin essential for the metabolism and function of brain cells—is thought to be one factor contributing to the cognitive deficits and brain pathology characteristic of WKS. Excessive alcohol consumption may contribute to thiamine deficiency in several ways. Studies in human patients and animal models of WKS are attempting to identify brain structures affected by thiamine deficiency and to correlate them with the cognitive deficits observed in WKS patients.
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spelling pubmed-68757312019-12-03 Alcohol-Related Thiamine Deficiency: Impact on Cognitive and Memory Functioning Langlais, Philip J. Alcohol Health Res World Articles Chronic alcohol abuse is associated with several neurological disorders, including Wernicke-Korsakoff syndrome (WKS). Deficiency of thiamine—a vitamin essential for the metabolism and function of brain cells—is thought to be one factor contributing to the cognitive deficits and brain pathology characteristic of WKS. Excessive alcohol consumption may contribute to thiamine deficiency in several ways. Studies in human patients and animal models of WKS are attempting to identify brain structures affected by thiamine deficiency and to correlate them with the cognitive deficits observed in WKS patients. National Institute on Alcohol Abuse and Alcoholism 1995 /pmc/articles/PMC6875731/ /pubmed/31798071 Text en http://creativecommons.org/publicdomain/mark/1.0/ Unless otherwise noted in the text, all material appearing in this journal is in the public domain and may be reproduced without permission. Citation of the source is appreciated.
spellingShingle Articles
Langlais, Philip J.
Alcohol-Related Thiamine Deficiency: Impact on Cognitive and Memory Functioning
title Alcohol-Related Thiamine Deficiency: Impact on Cognitive and Memory Functioning
title_full Alcohol-Related Thiamine Deficiency: Impact on Cognitive and Memory Functioning
title_fullStr Alcohol-Related Thiamine Deficiency: Impact on Cognitive and Memory Functioning
title_full_unstemmed Alcohol-Related Thiamine Deficiency: Impact on Cognitive and Memory Functioning
title_short Alcohol-Related Thiamine Deficiency: Impact on Cognitive and Memory Functioning
title_sort alcohol-related thiamine deficiency: impact on cognitive and memory functioning
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6875731/
https://www.ncbi.nlm.nih.gov/pubmed/31798071
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