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Noradrenergic signaling the wakeful state inhibits microglial surveillance and synaptic plasticity in the mouse visual cortex.
Microglia are the brain’s resident innate immune cells and also have a role in synaptic plasticity. Microglial processes continuously survey the brain parenchyma, interact with synaptic elements and maintain tissue homeostasis. However, the mechanisms that control surveillance and its role in synapt...
Autores principales: | Stowell, Rianne D., Sipe, Grayson O., Dawes, Ryan P., Batchelor, Hanna N., Lordy, Katheryn A., Whitelaw, Brendan S., Stoessel, Mark B., Bidlack, Jean M., Brown, Edward, Sur, Mriganka, Majewska, Ania K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6875777/ https://www.ncbi.nlm.nih.gov/pubmed/31636451 http://dx.doi.org/10.1038/s41593-019-0514-0 |
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