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Hypolipidemic and Antioxidant Activities of Corrigiola telephiifolia in Diabetic Rats
OBJECTIVE: The evaluation of the hypolipidemic and antioxidant activities of the aerial parts aqueous extract of Corrigiola telephiifolia (APAE of C. telephiifolia) in normal and streptozotocin (STZ)-induced diabetic rats. METHODS: The effects of oral administration of APAE of C. telephiifolia (5 mg...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Bentham Science Publishers
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6875864/ https://www.ncbi.nlm.nih.gov/pubmed/30827268 http://dx.doi.org/10.2174/1871525717666190227231834 |
| Sumario: | OBJECTIVE: The evaluation of the hypolipidemic and antioxidant activities of the aerial parts aqueous extract of Corrigiola telephiifolia (APAE of C. telephiifolia) in normal and streptozotocin (STZ)-induced diabetic rats. METHODS: The effects of oral administration of APAE of C. telephiifolia (5 mg/kg) on the lipid profile as well as the in vitro antioxidant activity of this aqueous extract have been determined. RESULTS: APAE of C. telephiifolia (5 mg/kg) reduced significantly (p<0.001) the plasma total cholesterol levels in diabetic rats. In contrast, no significant increase in plasma triglyceride levels in normal and in STZ-induced diabetic rats was observed. On the other hand, APAE of C. telephiifolia showed an antioxidant activity. CONCLUSION: The APAE of C. telephiifolia exhibits an antioxidant, cholesterol and body weight-lowering activities in diabetic rats. |
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