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Background characteristics and postoperative outcomes of insufficient weight loss after laparoscopic sleeve gastrectomy in Japanese patients

AIM: Laparoscopic sleeve gastrectomy (LSG) is becoming popular in Japan, but insufficient weight loss is often observed in patients after LSG. We investigated the effect of LSG on obesity‐related comorbidities and identified the background characteristics of Japanese patients with insufficient weigh...

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Autores principales: Saiki, Atsuhito, Yamaguchi, Takashi, Tanaka, Sho, Sasaki, Akira, Naitoh, Takeshi, Seto, Yasuyuki, Matsubara, Hisahiro, Yokote, Koutaro, Okazumi, Shinichi, Ugi, Satoshi, Yamamoto, Hiroshi, Ohta, Masayuki, Ishigaki, Yasushi, Kasama, Kazunori, Seki, Yosuke, Irie, Junichiro, Kusakabe, Toru, Tsujino, Motoyoshi, Shimizu, Hideharu, Shirai, Kohji, Onozaki, Akira, Kitahara, Aya, Hayashi, Karin, Miyazaki, Yasuhiro, Masaki, Takayuki, Nagayama, Daiji, Yamamura, Shigeo, Tatsuno, Ichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6875950/
https://www.ncbi.nlm.nih.gov/pubmed/31788652
http://dx.doi.org/10.1002/ags3.12285
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author Saiki, Atsuhito
Yamaguchi, Takashi
Tanaka, Sho
Sasaki, Akira
Naitoh, Takeshi
Seto, Yasuyuki
Matsubara, Hisahiro
Yokote, Koutaro
Okazumi, Shinichi
Ugi, Satoshi
Yamamoto, Hiroshi
Ohta, Masayuki
Ishigaki, Yasushi
Kasama, Kazunori
Seki, Yosuke
Irie, Junichiro
Kusakabe, Toru
Tsujino, Motoyoshi
Shimizu, Hideharu
Shirai, Kohji
Onozaki, Akira
Kitahara, Aya
Hayashi, Karin
Miyazaki, Yasuhiro
Masaki, Takayuki
Nagayama, Daiji
Yamamura, Shigeo
Tatsuno, Ichiro
author_facet Saiki, Atsuhito
Yamaguchi, Takashi
Tanaka, Sho
Sasaki, Akira
Naitoh, Takeshi
Seto, Yasuyuki
Matsubara, Hisahiro
Yokote, Koutaro
Okazumi, Shinichi
Ugi, Satoshi
Yamamoto, Hiroshi
Ohta, Masayuki
Ishigaki, Yasushi
Kasama, Kazunori
Seki, Yosuke
Irie, Junichiro
Kusakabe, Toru
Tsujino, Motoyoshi
Shimizu, Hideharu
Shirai, Kohji
Onozaki, Akira
Kitahara, Aya
Hayashi, Karin
Miyazaki, Yasuhiro
Masaki, Takayuki
Nagayama, Daiji
Yamamura, Shigeo
Tatsuno, Ichiro
author_sort Saiki, Atsuhito
collection PubMed
description AIM: Laparoscopic sleeve gastrectomy (LSG) is becoming popular in Japan, but insufficient weight loss is often observed in patients after LSG. We investigated the effect of LSG on obesity‐related comorbidities and identified the background characteristics of Japanese patients with insufficient weight loss after LSG. METHODS: In this multi‐institutional retrospective study at 10 certified bariatric institutions, 322 Japanese patients who underwent LSG with a follow‐up period of more than 2 years were analyzed. Anthropometry, obesity‐related comorbidities and psychosocial background data were collected. Weight loss was expressed as 2‐year percent total weight loss (%TWL). RESULTS: Mean age, body weight, body mass index (BMI) and glycated hemoglobin were 46.9 years, 119.2 kg, 43.7 kg/m(2) and 7.1%, respectively. Prevalence of mental disorders was 26.3%. Mean BMI declined to 30.3 kg/m(2) at 2 years and %TWL was 29.9%. Improvements in the markers and prevalence of obesity‐related comorbidities were observed. Remission rates of diabetes, dyslipidemia and hypertension were 75.6%, 59.7% and 41.8%, respectively. %TWL at the respective cut‐off level of diabetes remission was 20.8%. Lower remission rates of diabetes in patients with %TWL <20%, and less calorie restriction and higher prevalence of mental disorders (46.9%) in patients with %TWL <15% were observed. Frequencies of %TWL <15% and <20% were 6.5% and 18.5%, respectively. CONCLUSION: %TWL 20% was a candidate cut‐off point of insufficient weight loss for diabetes remission after LSG, and mental disorders might be relevant to intractable obesity in Japanese patients.
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spelling pubmed-68759502019-11-29 Background characteristics and postoperative outcomes of insufficient weight loss after laparoscopic sleeve gastrectomy in Japanese patients Saiki, Atsuhito Yamaguchi, Takashi Tanaka, Sho Sasaki, Akira Naitoh, Takeshi Seto, Yasuyuki Matsubara, Hisahiro Yokote, Koutaro Okazumi, Shinichi Ugi, Satoshi Yamamoto, Hiroshi Ohta, Masayuki Ishigaki, Yasushi Kasama, Kazunori Seki, Yosuke Irie, Junichiro Kusakabe, Toru Tsujino, Motoyoshi Shimizu, Hideharu Shirai, Kohji Onozaki, Akira Kitahara, Aya Hayashi, Karin Miyazaki, Yasuhiro Masaki, Takayuki Nagayama, Daiji Yamamura, Shigeo Tatsuno, Ichiro Ann Gastroenterol Surg Original Articles AIM: Laparoscopic sleeve gastrectomy (LSG) is becoming popular in Japan, but insufficient weight loss is often observed in patients after LSG. We investigated the effect of LSG on obesity‐related comorbidities and identified the background characteristics of Japanese patients with insufficient weight loss after LSG. METHODS: In this multi‐institutional retrospective study at 10 certified bariatric institutions, 322 Japanese patients who underwent LSG with a follow‐up period of more than 2 years were analyzed. Anthropometry, obesity‐related comorbidities and psychosocial background data were collected. Weight loss was expressed as 2‐year percent total weight loss (%TWL). RESULTS: Mean age, body weight, body mass index (BMI) and glycated hemoglobin were 46.9 years, 119.2 kg, 43.7 kg/m(2) and 7.1%, respectively. Prevalence of mental disorders was 26.3%. Mean BMI declined to 30.3 kg/m(2) at 2 years and %TWL was 29.9%. Improvements in the markers and prevalence of obesity‐related comorbidities were observed. Remission rates of diabetes, dyslipidemia and hypertension were 75.6%, 59.7% and 41.8%, respectively. %TWL at the respective cut‐off level of diabetes remission was 20.8%. Lower remission rates of diabetes in patients with %TWL <20%, and less calorie restriction and higher prevalence of mental disorders (46.9%) in patients with %TWL <15% were observed. Frequencies of %TWL <15% and <20% were 6.5% and 18.5%, respectively. CONCLUSION: %TWL 20% was a candidate cut‐off point of insufficient weight loss for diabetes remission after LSG, and mental disorders might be relevant to intractable obesity in Japanese patients. John Wiley and Sons Inc. 2019-08-26 /pmc/articles/PMC6875950/ /pubmed/31788652 http://dx.doi.org/10.1002/ags3.12285 Text en © 2019 The Authors. Annals of Gastroenterological Surgery published by John Wiley & Sons Australia, Ltd on behalf of The Japanese Society of Gastroenterological Surgery This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Articles
Saiki, Atsuhito
Yamaguchi, Takashi
Tanaka, Sho
Sasaki, Akira
Naitoh, Takeshi
Seto, Yasuyuki
Matsubara, Hisahiro
Yokote, Koutaro
Okazumi, Shinichi
Ugi, Satoshi
Yamamoto, Hiroshi
Ohta, Masayuki
Ishigaki, Yasushi
Kasama, Kazunori
Seki, Yosuke
Irie, Junichiro
Kusakabe, Toru
Tsujino, Motoyoshi
Shimizu, Hideharu
Shirai, Kohji
Onozaki, Akira
Kitahara, Aya
Hayashi, Karin
Miyazaki, Yasuhiro
Masaki, Takayuki
Nagayama, Daiji
Yamamura, Shigeo
Tatsuno, Ichiro
Background characteristics and postoperative outcomes of insufficient weight loss after laparoscopic sleeve gastrectomy in Japanese patients
title Background characteristics and postoperative outcomes of insufficient weight loss after laparoscopic sleeve gastrectomy in Japanese patients
title_full Background characteristics and postoperative outcomes of insufficient weight loss after laparoscopic sleeve gastrectomy in Japanese patients
title_fullStr Background characteristics and postoperative outcomes of insufficient weight loss after laparoscopic sleeve gastrectomy in Japanese patients
title_full_unstemmed Background characteristics and postoperative outcomes of insufficient weight loss after laparoscopic sleeve gastrectomy in Japanese patients
title_short Background characteristics and postoperative outcomes of insufficient weight loss after laparoscopic sleeve gastrectomy in Japanese patients
title_sort background characteristics and postoperative outcomes of insufficient weight loss after laparoscopic sleeve gastrectomy in japanese patients
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6875950/
https://www.ncbi.nlm.nih.gov/pubmed/31788652
http://dx.doi.org/10.1002/ags3.12285
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